Publications

Peer-Reviewed Publications

  • Cheriyath, V., Kuhns, M., Jacobs, B., Evangelista, P., Downs-Kelly, E., Tubbs, R., Crowe, J., and Borden, E.C. G1P3, an interferon- and estrogen-induced survival protein contributes to hyperplasia, tamoxifen resistance and poor outcomes in breast cancer. Oncogene. 2011. Epub 2011/10/15. doi: 10.1038/onc.2011.393. PubMed PMID: 21996729.
    • Primary Corresponding author
  • Cheriyath, V., Leaman, D.G. and Borden, E.C. Emerging Roles of FAM14 Family Members (ISG 6-16 and ISG 12) in Innate Immunity and Cancer. J. Interferon and. Cyto. Res., 2011, 31:173-81.
    • Primary and Corresponding author
  • Cheriyath, V., Kuhns, M., Kalaycio, M.E. and Borden, E.C. Potentiation of apoptosis by histone deacetylase inhibitors and doxorubicin combination: cytoplasmic cathepsin B as a mediator of apoptosis in multiple myeloma. Br. J. Cancer, 2011, 104: 957-67.
    • Primary and Corresponding author
  • Luszczek, W., Cheriyath, V., Borden, E.C., Mekhail, T. Combinations of DNA Methyltransferase and Histone Deacetylase Inhibitors Induce DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance to Interferon Stimulated Gene Expression. Mol. Cancer Ther., 2010, 9:2309-21.
  • Bae, S., V. Cheriyath, B. Jacobs, F. Reu, and E. Borden. Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL. Oncogene, 2008, 27: 490 – 498.
    • Co-First author.
  • Cheriyath, V., K. B. Glaser, J. F. Waring, R. Baz, M. A. Hussein, and E. C. Borden. G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells. J Clin Invest., 2007, 117: 3107-3117.
  • Cheriyath, V., Jacobs, B.S. and Hussein, M.A. Proteasome inhibitors in the Clinical Setting: Benefits and Strategies to Overcome Multiple Myeloma Resistance to Proteasome Inhibitors. Drugs R D., 2007, 8: 1-12.
  • Cheriyath, V. and Hussein, M.A. Osteopontin, angiogenesis and multiple myeloma. Leukemia, 2005, 19: 2203-5
  • Corresponding author
  • Cheriyath, V., Desgranges, Z.P. and Roy, A.L. c-Src-dependent transcriptional activation of TFII-I, J. Biol. Chem., 2002, 277: 22798-22805.
  • Cheriyath, V., Balasubrahmanyam, A. and Kapoor, H.C. Purification and characterization of a 29 kDa poly(A)-binding protein from chickpea (Cicer arietinum) epicotyl, Indian J. Biochem. Biophys., 2001, 38: 258-262.
  • Cheriyath, V. and Roy, A.L. Structure-function analysis of TFII-I. Roles of the N-terminal end, basic region, and I-repeats, J. Biol. Chem., 2001, 276: 8377-8383.
  • Parker, R., Phan, T., Baumeister, P., Roy, B., Cheriyath, V., Roy, A.L. and Lee, A.S. Identification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interaction with ATF6, Mol. Cell Biol., 2001, 21: 3220-3233.
  • Cheriyath, V., Balasubrahmanyam, A. and Kapoor, H.C. Purification and characterization of a poly(A)-binding protein from chickpea (Cicer arietinum) epicotyl, Indian J. Biochem. Biophys., 2000, 37: 107-113.
  • Cheriyath, V. and Roy, A.L. Alternatively spliced isoforms of TFII-I. Complex formation, nuclear translocation, and differential gene regulation, J. Biol. Chem.,2000, 275: 26300-26308.
  • Novina, C.D., Kumar, S., Bajpai, U., Cheriyath, V., Zhang, K., Pillai, S., Wortis, H.H. and Roy, A.L. Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton’s tyrosine kinase, Mol. Cell Biol., 1999, 19: 5014-5024.
  • Cheriyath, V., Novina, C.D. and Roy, A.L. TFII-I regulates Vbeta promoter activity through an initiator element, Mol. Cell Biol., 1998, 18: 4444-4454.
  • Kapoor, H.C., Venugopalan, C. and Sharma, N. Indian Journal of Experimental Biology., 1998, 36: 501-505.
  • Kim, D.W., Cheriyath, V., Roy, A.L. and Cochran, B.H. TFII-I enhances activation of the c-fos promoter through interactions with upstream elements, Mol. Cell Biol., 1998, 18: 3310-3320.
  • Novina, C.D., Cheriyath, V. and Roy, A.L. Regulation of TFII-I activity by phosphorylation, J. Biol. Chem., 1998, 273: 33443-33448.
  • Grueneberg, D.A., Henry, R.W., Brauer, A., Novina, C.D., Cheriyath, V., Roy, A.L. and Gilman, M. A multifunctional DNA-binding protein that promotes the formation of serum response factor/homeodomain complexes: identity to TFII-I, Genes Dev., 1997, 11: 2482-2493.
  • Novina, C.D., Cheriyath, V., Denis, M.C. and Roy, A.L. Methods for studying the biochemical properties of an Inr element binding protein: TFII-I, Methods, 1997, 12: 254-263.
  • Venugopalan, C. and Kapoor, H.C. Single step isolation of plant RNA, Phytochemistry, 1997, 46: 1303-1305.
  • Venugopalan, C. and Srivastava, K.N. Ind. J. Food Science & Tech, 1996, 33: 389-392.

Abstracts

  • Jankowska, A.M., Szpurka, H., Cheriyath, V., Ng, K., Hu, Z., McDevitt, M., Saunthararajah, Y. and Maciejewski, J.P. Consequences of UTX Dysfunction in Myelodysplastic Syndrome (American Soeciety of Hematology). 2011
  • Makishima, H., Khan, S., Jankowska, A., Sugimoto, Y., Zhenbo Hu, Z., Cheriyath, V., Mahfouz, R., Ebrahem, Q., Vatolin, S. and Saunthararajah. Y., et al. EZH2 Is Either Mutated or Downregulated in Patients with Loss of Heterozygosity of Chromosome 7/7q and Leads to Epigenetic Dysregulation Via Histone H3K27. (American Soeciety of Hematology). 2011
  • Kuhns, M., Kalaycio, M., Reu, F., Maciejewski, J. and Cheriyath, V. GSK-3β Inhibitors in Over-coming Chemoresistance in Multiple Myeloma. ASH Annual Meeting. 2010.
  • Cheriyath, V., Kuhns, M., Kalaycio, M and Borden, E.C. Inflammatory signaling genes as predictive markers of vorinostat sensitivity in multiple myeloma. AACR Annual Meeting, 2010.
  • Luszczek, W., Cheriyath, V., Mekhail, T., Borden, E.C. 5-AZA-dC and HDAC Inhibitor Combination Induced DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance to Interferon Stimulated Gene Expression. AACR Annual Meeting-2010.
  • Cheriyath, V., Luszczek, W., Jacobs, B.S. and Borden, E.C. Interferon (IFN)-stimulated genes (ISGs) as a resistance mechanism in cancer cell death. Tri-Society Annual Conference: Cellular and Cytokine Interactions in Health and Disease -2009.
  • Cheriyath, V., Jacobs, B.S., Kuhns, M., Evangelista, P.J., Budd, T.G., Crowe, J.P., Tubbs, R.R., and Borden, E.C. Molecular Role of the Antiapoptotic Protein G1P3 in Cytokine and Endo-crine Mediated Survival Signaling in Breast Cancer Cells. AACR Annual Meeting -2009.
  • Luszczek, W., Cheriyath, V., Mekhail, T., Borden, E.C. Synergistic interaction of 5-aza-deoxycytidine (5-AZA-dC) and histone deacetylase (HDAC) inhibitor MGCD0103 in small cell lung cancer (SCLC) cells. AACR Annual Meeting-2009.
  • Mahindra, A., Jacobs, B.S., Kalaycio., M., Borden, E.C. and Cheriyath, V. Epigenetic modulators in combination with doxorubicin in multiple myeloma – 2009
  • Cheriyath, V., Thomas, DG, Baz, R., Kalaycio, M and Borden EC. HDAC inhibitor plus doxorubicin combinations reverse apoptosis resistance in myeloma cells by triggering cathepsin mediated BAX activation, ASH Annual Meeting, 2008.
  • Cheriyath, V., Thomas, DG, Glaser, KB, Greenberg, CH et.al., Epigenetic regulation of IFN- α2b activity in multiple myeloma by a non-hydroxamate HDAC inhibitor A-423378. AACR Annual Meeting -2008.
  • Luszczek, W., Cheriyath, V., Mekhail, T., Borden, E.C., Effects of 5-aza-deoxycytidine (5-AZA-dC) and histone deacetylase (HDAC) inhibitors on proliferation and gene expression in small cell lung cancer cells. AACR Annual Meeting -2008.
  • Cheriyath, V., Glaser, K.B., Greenberg, C.H., Kalaycio, M. and Borden, E.C. Epigenetic Regulation of IFN- α2b in Multiple Myeloma by a Hydroxamic Acid Histone Deacetylase (HDAC) Inhibitor (SAHA) and a non-Hydroxamic Acid HDAC Inhibitor (A-423378). 43rd ASCO Annual Meeting, June 1-5, 2007.
  • Cheriyath, V., Hussein, M.A., Glaser, K.B., Greenberg, C.H. and Borden, E.C. G1P3 (ISG6-16), an Interferon (IFN) stimulated survival factor antagonizes Apo2L/TRAIL induced apoptosis in myeloma cells. AACR Centennial Meeting, April 14-18, 2007.
  • Cheriyath, V., Hussein, M.A. and Borden, E.C. G1P3 an Interferon Stimulated Gene (ISG) antagonizes TRAIL induced apoptosis in Myeloma. Cytokine 2006,ISICR, meeting, Vienna, 2006.
  • Cheriyath, V., Hussein, M.A. and Borden, E.C. Epigenetically Regulated Interferons Activity in Multiple Myeloma by Histone Deacetylase Inhibitors, 97th AACR Annual Meeting, April 1-5, 2006.
  • Cheriyath, V., Nguyen, H., MacLeod, R., Hussein, M.A. and Borden, E.C. Epigenetically Regulated Interferons Activity in Multiple Myeloma by Isotype-Selective HDAC inhibitor MGCD0103. Clin. Cancer Res. 11 [24 Suppl], 9006s. 12-15, 2005.
  • Cheriyath, V., Hussein, M.A. and Borden, E.C. Epigenetically Regulated Interferon (IFN) Stimulated Genes: Potential Role in Augmenting the Antigrowth Activity of IFNs in Multiple Myeloma, 96th AACR Annual Meeting, 2005.
  • Cheriyath, V., Hussein, M.A. and Borden, E.C. Epigenetic Regulators: Potential Role in Augmenting IFNs antitumor Effects in Multiple Myeloma., Think Tank on Molecular Targets in Lymphoid Malignancies, 2005.
  • Cheriyath, V., Nguyen, H., Macleod, R.A., Hussein, M.A. and Borden, E.C. Epigenetic Regulation of IFN Activity in Multiple Myeloma by the Isotype-Selective HDAC Inhibitor MGCD0103., AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics: Discovery, Biology, and Clinical Applications, Philadelphia, 2005.
  • Masci, P., Cheriyath, V., Wood, L., Rybicki, L., Jacobs, B., Williams, B.R., Faber, P., Burkowski, R., Tong, K. and Borden, E.C. Clinical and Biological Evaluation of IFN alpha-1b: Gene Modulation and Clinical Effects, International Society for Interferon and Cytokine Research, 2005.
  • Cheriyath, V. and Roy, A.L. Role of Src in Internalization and Nuclear Sorting of the Transcription factor TFII-I, Cold Spring Harbor Laboratory-Tyrosine Phosphorylation and Cell Signaling, 2001.
  • Cheriyath, V. and Roy, A.L. Role of Src in Activation and Nuclear translocation of the Transcription factor TFII-I, Keystone Symposia – The Molecular Basis of Cancer: Signaling to Cell Growth and Death, 2001.
  • Gruenberg, D.A., Henry, R.W., Brauer, A., Novina, C.D., Cheriyath, V. and Roy, A.L. A Multifunctional DNA-Binding Protein that Promotes the Formation of Serum Response Factor/Homeodomain Complexes, Identity to TFII-I, Cold Spring Harbor Laboratory-Mechanisms of Eukaryotic Transcription, 1997.
  • Kim, D.W., Cheriyath, V., Roy, A.L. and Cochran, B.H. TFII-I Enhances Activation of the c-Fos Promoter and Forms a Complex with SRF, Cold Spring Harbor Laboratory-Mechanisms of Eukaryotic Transcription, 1997.
  • Novina, C.D., Bajpai, U., Cheriyath, V., Wortis, H.H. and Roy, A.L. Processing of Induced Signals into Transcriptional Responses via TFII-I, Cold Spring Harbor Laboratory-Mechanisms of Eukaryotic Transcription, 1997.
  • Venugopalan, C. and Kapoor, H.C. 2nd International Crop Science Congress, 1996.